To The Rescue! is a charming dog shelter simulator. Take care of unique dogs and find the right homes for as many of them as you can. Upgrade your shelter, control disease outbreaks, learn each dog's preferences, and make tough decisions, all while helping support real-world animal shelters! Each day brings new challenges and rewards. Dogs have specific preferences, can get infectious diseases, and can have negative traits. But you can also have fundraisers, get random donations, and help someone find their new best friend. Unfortunately, there's never enough room, and always more dogs.

In To The Rescue!'s main story mode you can progress from housing dogs in your own garage to running a giant, efficient shelter of your own. There will always be events that keep you on your toes, and story threads that develop between them.